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Bextra Side Effects - New York Lawyers
Bextra (valdecoxib) is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Valdecoxib works by reducing substances in the body that cause inflammation, pain, and fever, and is used to reduce pain, inflammation, and stiffness caused by osteoarthritis and adult rheumatoid arthritis.

Bextra’s label already warns against serious skin reactions as a possible side effect, and some trials found an increased risk of unspecified “cardiovascular events” in Bextra patients who had cardiac bypass surgery.

Prescription nonsteroidal anti-inflammatory drugs (NSAIDs), such as Bextra (valdecoxib) are one of the leading classes of drugs that cause Stevens Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and erythema multiforme (EM) due to drug allergy reactions. Bextra has also been linked to possible cardiac problems including heart attacks and strokes.

In October 2004, Pfizer announced that two clinical trials showed heart bypass surgery patients taking Bextra increased their risk of stroke and heart attack. The news came just weeks after the FDA withdrew Vioxx, a similar COX-2 inhibitor, from the market due to an increased risk of cardiovascular events.


Possible Bextra Side Effects
  • Application site disorders: Cellulitis, dermatitis contact
  • Cardiovascular: Aggravated hypertension, aneurysm, anginapectoris, arrhythmia, cardiomyopathy, congestive heart failure, coronary artery disorder, heart murmur, hypotension
  • Central, peripheral nervous system: Cerebrovascular disorder, hypertonia, hypoesthesia, migraine, neuralgia, neuropathy, pares-thesia, tremor, twitching, vertigo
  • Endocrine: Goiter
  • Female reproductive: Amenorrhea, dysmenorrhea, leukorrhea, mastitis, menstrual disorder, menorrhagia, menstrual bloating, vagi-nal hemorrhage
  • Gastrointestinal: Abnormal stools, constipation, diverticulosis, dry mouth, duodenal ulcer, duodenitis, eructation, esophagitis, fecal incontinence, gastric ulcer, gastritis, gastroenteritis, gastroe-sophageal reflux, hematemesis, hematochezia, hemorrhoids, hem-orrhoids bleeding, hiatal hernia, melena, stomatitis, stool frequency increased, tenesmus, tooth disorder, vomiting
  • General: Allergy aggravated, allergic reaction, asthenia, chest pain, chills, cyst NOS, edema generalized, face edema, fatigue, fever, hot flushes, halitosis, malaise, pain, periorbital swelling, peripheral pain Hearing and vestibular: Ear abnormality, earache, tinnitus
  • Heart rate and rhythm: Bradycardia, palpitation, tachycardia
  • Hemic: Anemia
  • Liver and biliary system: Hepatic function abnormal, hepatitis, ALT increased, AST increased
  • Male reproductive: Impotence, prostatic disorder
  • Metabolic and nutritional: Alkaline phosphatase increased, BUN increased, CPK increased, creatinine increased, diabetes mellitus, glycosuria, gout, hypercholesterolemia, hyperglycemia, hyperkalemia, hyperlipemia, hyperuricemia, hypocalcemia, hypokalemia, LDH increased, thirst increased, weight decrease, weight increase, xerophthalmia
  • Musculoskeletal: Arthralgia, fracture accidental, neck stiffness, osteoporosis, synovitis, tendonitis
  • Neoplasm: Breast neoplasm, lipoma, malignant ovarian cyst
  • Platelets (bleeding or clotting): Ecchymosis, epistaxis, hematoma NOS, thrombocytopenia
  • Psychiatric: Anorexia, anxiety, appetite increased, confusion, depression, depression aggravated, insomnia, nervousness, morbid dreaming, somnolence
  • Resistance mechanism disorders: Herpes simplex, herpes zoster, infection fungal,infection soft tissue, infection viral, moniliasis, moniliasis genital, otitis media
  • Respiratory: Abnormal breath sounds, bronchitis, bronchospasm, coughing, dyspnea, emphysema, laryngitis, pneumonia, pharyngitis, pleurisy, rhinitis
  • Skin and appendages: Acne, alopecia, dermatitis, dermatitis fun-gal, eczema, photosensitivity allergic reaction, pruritus, rash ery-thematous, rash maculopapular, rash psoriaform, skin dry, skin hypertrophy, skin ulceration, sweating increased, urticaria
  • Special senses: Taste perversion
  • Urinary system: Albuminuria, cystitis, dysuria, hematuria, micturition frequency increased, pyuria, urinary incontinence, urinary tract infection
  • Vascular: Claudication intermittent, hemangioma acquired, varicose vein
  • Vision: Blurred vision, cataract, conjunctival hemorrhage, con-junctivitis, eye pain, keratitis, vision abnormal
  • White cell and RES disorders: Eosinophilia, leukopenia, leukocytosis, lymphadenopathy, lymphangitis, lymphopenia

There may be additional undocumented Bextra side effects.

If you are experiencing any of the above listed side effects, and have taken Bextra, contact Belluck & Fox immediately for a free legal evaluation. Drug litigation can be extremely complex. It is best to seek the counsel of a personal injury attorney with experience in this field of law. Belluck & Fox has substantial experience with defective product litigation, including pharmaceutical and medical product cases. We will provide you with personalized, professional legal representation.

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295 Madison Avenue, 37th Floor
New York, New York, 10017
Phone: 212-681-1575
Toll Free: 1-877-NYLAW08
Fax: 212-681-1574
Email: bfinfo@belluckfox.com
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